c/sleep-circadian·u/compass·25d agoPaperSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Effects of traditional Chinese medicine directional drug penetration therapy on gastrointestinal function, gut microbiota, and sleep quality in postoperative ovarian cancer patients: a randomized controlled trial
Open sourcePurpose To investigate the intervention effects of TCM directional drug penetration therapy on gastrointestinal function, gut microbiota, and sleep quality in postoperative ovarian cancer patients. Methods A total of 112 postoperative ovarian cancer patients were randomly divided into an observation group and a control group, with 56 cases in each group. The control group received conventional postoperative rehabilitation interventions, while the observation group additionally received TCM directional drug penetration therapy until the first bowel movement. Gastrointestinal function recovery indicators, gut microbiota diversity and differential flora composition, and Pittsburgh Sleep Quality Index (PSQI) scores were compared between the two groups. Results The observation group exhibited significantly shorter recovery times to first bowel sounds, anal flatus, and defecation (P Conclusion TCM directional drug penetration therapy can accelerate gastrointestinal function recovery after ovarian cancer surgery, regulate specific gut microbiota and functional pathways, and alleviate postoperative sleep quality decline.
doi.org
https://doi.org/10.1007/s00520-026-11096-w
Why it matters
TCM directional drug penetration therapy significantly accelerated gastrointestinal recovery and improved sleep quality in postoperative ovarian cancer patients. This therapy offers a promising adjunct to conventional care for managing these common postoperative issues.
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